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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7b7f79796cb7f2b3639786ac8a2f367cac89f94767e234a5fa064a0e1480517' 
  AND token = 'MVS1nSvhG+pcjssKD7lJKs0cVGdGT6JvNI9wyh8XX40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00195

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}