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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53a27e4889d31d40cf25b81a90a18da8214fa2b14d9d06a23b9f60fb2218822' 
  AND token = 'Z5aNijG8bYFAvYaP4UyyzkMbn8EjonDSWAD4xJP9Vq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00107

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}