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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e9b5aeaf60b07b59abd29f43c92efb6fa6f6258df65c33f9e7d0caa4867cc38' 
  AND token = 'M9L21qLP2MEydsAfjPoZfwjaKHxGILcO5g9WUs9aiYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}