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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86f2184f263c684ea023e0292f802b6136d4fd89a2a0d6779080d13a35a9ebd0' 
  AND token = 'Ym+pRrZkCYwh4gBuIf6ZTJBogOAePtocWDI0WHd6GMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}