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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18aeacfb6dd22a786742acd6c5cc59714744dad2f978a7f6317e51dec5ace467' 
  AND token = 'iaht4kmRPkiN4URaR4N8HMFFvQPdJk2d3ZnoYpq/PxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}