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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7429b1bbc2cb19997ed19dd18dbcec0936f01df18d5b1937ef13aa02c61c37' 
  AND token = 'q2q4h45D1l98tNhRNUA+1074d91FSVa8iOS59xSTR4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}