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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f44adc7e710598571e4a239eb0b91a7a3497dcca8c45fbac8572026dcb5859a' 
  AND token = 'w4P+KqDRikT8tbwLyz9C3MiA5IECyn4HmTQbRT9CUJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}