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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df2b966d9ad93cf7944a95a500100f2e41b43d5be005bf640c91be7bb352ba75' 
  AND token = 'PPhAK+ee+o74MZOT1+y8qsUDU9S8EAjb6nj/zO6GVJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}