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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c599f4f57a7298aa74b8284e77ac7d11a072dc2fe6eee61bc6e8bca3af5a5109' 
  AND token = 'tyCEifl5KAKsPMnr8WiHTMdFIWgH+WS3qJMnjE3gr+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}