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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e78da35968c1071a39e75d2c8823af552c032cbcfa81345d0bf49d5a485848f' 
  AND token = 'NNY6OfX9Blfp3C0Zes4qNifpMMr7N2MF1Q3wSHgfhPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}