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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d49ffa7e7b88446b2f43bbfba58191268e8fa0dbf925e36d047451afb19d71' 
  AND token = 'ysyXGt4uY/BPrVEKH3oxMELictfxybC62jYF+rCerzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}