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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d42eed547e17aef8a8f7f304472e6b0de51a62dbf3af80ac3ca03b87bcad1b2' 
  AND token = 'BEcKMdSNUrlAifFaw07rWdQWBJtj+9miSVRzUZ7h5ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}