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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67615adddbded61b6cb601aff4903c283ceffd9a74a4dced5df39068218e2187' 
  AND token = 't0DDscKRpAqXAsSjH7FHtfaIgUdql6k/BePuDk5K1bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}