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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151fa3e33803237b7342726d36a032c8c5726e89ac2adfc49e163a0a2011b1c0' 
  AND token = 'nZzfe+9s7Cn7KHjoMq0N9JAvUm0Amdr8g6jUitiF3PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}