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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a549fb19808097a60f1a9df497d8eeb2e1bfdb709faa4d8555538c5b80f9a8f' 
  AND token = 'ILr1E8HetsGHM02DHWsHJsmwDw5VzZT9/xvH9pHUv+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}