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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54811953c07ce47b8a66d3663b20d33178285bf77d9fdfe839439471bd40303' 
  AND token = 'B8BcfzamxUahF0CnrUAkTOLU65sE1UkpfWMYURW0Yho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}