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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b585502d7a7fdb45b77ea9e27384ac133d48c48664d2303aa78810a858e5f6' 
  AND token = 'ind+Gvub9GfXLAaZe/8MxGqxMv6xhGUCZanV3A4PvM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}