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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed0561b9973b877c13b79eed86e462ce40ea57340b83906da7b48c2ff42964b' 
  AND token = 'omu5VuEVnv+Yf4z7X+8PbEzRX9y19OGAvQb3mKNWqis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}