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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ba149d205fedcd500f1a7fe3a85428e39484dd56bdbd5308084f0c494053fb' 
  AND token = 'f2r4a4p2fY7xRUAngjU8pJ02N50RIVsxq2GBoN6++9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}