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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78d8c944d36a6add71285614b1b47d78af317b3eb627a82780273f6243b646a' 
  AND token = 'zulhmrL0PeedDVIiRMu4LB//Sbsm0QzQcur0Oeoxjcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}