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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f05abbbd939e5273641fbf8b21b73a86932cf9fdb6d866924ca9446d6d05f7e' 
  AND token = 'U8Cz6jtQ7HLiY58iC3kSIi40Qr5qBFhtQRpbj6CTL9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}