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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '974307e216d7d1cbfc56227b40042571849593cf575c0d7c2f127b15418a7b9f' 
  AND token = '+x5KpUWWefaM0JSiNzeJZL3DEnbL/NwOjLtaKcNnlLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}