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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '411b0b327b8e873c05ae17d486ae30fc22fc6b53c2840ee8f598ee2e5c60f2ca' 
  AND token = 'w6LAlJbtw/iTaS8Q3hO7/V1PWiOQ+XehZZXiI68j4Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}