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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '312e4fa61a0e2704f992b9bfafa3d871b3f3f4a5b7160b83bc5ba94f66185508' 
  AND token = '0uyLCtZbie9FGCCFhbiktpYr3d+5Yuo6JkwwSkf2bLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}