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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc34007027b5fe1e89bea9af029cc5ecc400a94517d72d32f9490881e01f97fc' 
  AND token = 'arV/dBCNJNO0lX0RQi8Aw4UH50icCeuTRF9+CHV3EtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}