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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e9bc2b0186f3c632626ca95f38648b6dba7a8405850b57bf173d1ce1a945097' 
  AND token = 'R226C6JjxzPVTo8cM4D1JOtv0pJXakVKO5gB7XMSPRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}