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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f7c7423bf37aa91dfd77284beab5ddc713aca33f6b8f12bbe517a25b9c6cdeb' 
  AND token = 'FxD+RSZZrW3c6kn1y+ZJJTJ2BwTrQfd+10FaEbNxAIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}