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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e825542009ea687be6c6cbf7775e9f01f798e13158dc7ac6aa5698e400494cfd' 
  AND token = '7VXQE0GfotJgMTpqsKXxzUS05BmurzNXpNJi8p9KYpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}