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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b33f730765ac98ab5233e4c4e292106b281a9c2a8ee160410e63cbc0ff8bf0' 
  AND token = 'GRc3SyYetBVZVRIA3eKpxRuEA2KZd3M40OxkORjmrC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}