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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db55bd04d4a5ac342d77fcf7e34f41362307c04df3f2e6415bd817100e25401' 
  AND token = 'WrKmsy0nYg2DtRvxerSM2QYcz1n/lzT8czUwDjvNC6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}