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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b509c4a94c63e796a3c19b4066316f8020399e416cd85fd2c7da94cabeab665' 
  AND token = '8UdqqEYyvqQNfIJLtVbRa/5OH0e6g4UxzL4OGP0fgek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}