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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec1e5966e326b5df3c0277d6749fd4361ff66cc897e66f5111538b8c299ecf6' 
  AND token = 'Dt9mSIagiYr8vTRQkAKmv3UWbcE3NCPc98E+NN8E71I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}