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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a7f8d3052fe225a22440bb7dd5147b29046c72201274eed9f98fbb919c6335' 
  AND token = 'civ4X1jGL0NRYRPWD0TGvJ3cNBkaVsoslZWR/RhIssU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}