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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '442a488da9599063b78ae4c64cc0395c4e054d47aaefb81ea84c868e91fd1149' 
  AND token = 'VTzIjUeaAOh9huSjZ53Nq7+qb2uOYiYnWvCsQ5UgR5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}